- Brand: GSK
- Product Code: GSK_DUD
- Availability: In Stock
Contain 2 active ingredients : Dutasteride 0.5 mg and Tamsulosin 0.4 mg. Both of these act on the prostate gland.
The prostate gland, which is found only in men, lies at the top of the tube connecting the bladder to the outside (urethra). The prostate gland often enlarges with advancing age (benign prostatic hyperplasia), pressing on the urethra and obstructing the flow of urine from the bladder. This can cause various urinary symptoms, such as difficulty passing urine.
Tamsulosin is a type of medicine called an alpha-blocker. It works by blocking alpha receptors that are found in the muscle in the prostate gland. This action causes the muscle in the prostate to relax, which relieves pressure on the urethra and allows urine to flow freely past the prostate.
Dutasteride is a type of medicine called a 5-alpha reductase inhibitor. It works by inhibiting the action of an enzyme in the body called 5-alpha reductase. This enzyme converts the male hormone testosterone into dihydrotestosterone (DHT), which is a more active form of testosterone. The enlargement of the prostate gland is dependent upon testosterone being converted to DHT within the prostate gland. In the absence of DHT, the prostate gland shrinks. By reducing the amount of testosterone converted into DHT, dutasteride helps to shrink the prostate gland.
The combined actions of relaxing the muscles in the prostate gland and shrinking the prostate gland relieve the pressure on the bladder and urethra. This allows urine to flow freely past the prostate and relieves the urinary symptoms associated with an enlarged prostate gland.
What is it used for?
Enlarged prostate gland (benign prostatic hyperplasia).
Combodart is used to relieve moderate to severe symptoms of BPH and to reduce the risk of developing a complete inability to pass urine (acute urinary retention) that may require surgery.
English instruction leaflet inside the box.
Size : 30 tablets / box