Contain the active ingredient: Rifampicin, which is a type of medicine called a rifamycin antibiotic. Rifampicin is most frequently used to treat tuberculosis (TB), but can also be used to treat infections caused by certain other bacteria. Rifampicin is also available without a brand name, ie as the generic medicine.
Rifampicin works by killing the bacteria that are causing the infection. It does this by targeting and inactivating a bacterial enzyme called RNA-polymerase. The bacteria use RNA-polymerase to make essential proteins and to copy their own genetic information (DNA). Without this enzyme the bacteria cannot reproduce and they die.
There are two stages in the treatment for tuberculosis. In the first two months treatment is aimed at killing as many bacteria as possible. Therefore several anti-TB drugs with different mechanisms of action are used at the same time (usually rifampicin, pyrazinamide, isoniazid and ethambutol). After this time some of the medicines are stopped and the others (usually rifampicin and isoniazid) are continued for a further four months to kill any remaining bacteria. Rifampicin is used in both stages of treatment.
The bacteria that cause TB are difficult to treat. By using several medicines at the same time, the bacteria can be targeted in different ways and hence treatment is more likely to be effective than using a single medicine. In addition, using different medicines together makes it less likely that bacteria will develop resistance to the treatment.
Rifampicin can also be used to treat infections such as brucellosis, leporosy, legionnaire's disease and serious infections caused by Staphylococcal bacteria. As for TB, when treating these infections, rifampicin should be used in combination with another antibiotic to prevent resistance occuring.
Rifampicin is also used to prevent certain types of meningitis in people who have been exposed to the infection.
What is it used for?
Treatment of tuberculosis (in combination with other anti-tuberculosis medicines).
Leprosy (in combination with at least one other anti-leprosy medicine).
Infections caused by Brucella bacteria (brucellosis) (in combination with other antibiotics).
Legionnaires' disease (in combination with other antibiotics).
Treatment of serious infections caused by Staphylococcal bacteria (in combination with other antibiotics).
Prevention of meningococcal meningitis.
Prevention of infection and disease caused by Haemophilus influenzae type B bacteria.
Size : 10 x 10's = 100 tablets / box