Orfarin 5 mg
- Brand: Orion
- Product Code: OR_OFR5
- Availability: In Stock
Contain the active ingredient : Warfarin which is a type of medicine called an oral anticoagulant. It is used to stop blood clots forming inside the blood vessels. It also stops blood clots that have already formed from getting bigger.
What is it used for?
Treating and preventing blood clots in the veins of the leg (deep vein thrombosis).
Treating and preventing blood clots in the lungs (pulmonary embolism).
Preventing blood clots from developing in conditions that have an increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves.
Preventing further blood clots that could cause a stroke in people who have had a mini-stroke (transient ischaemic attack).
Why are blood clots dangerous?
Blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. However, a blood clot that forms abnormally inside the blood vessels (known as a thrombus) can be dangerous because it can block the blood vessel. The clot may also detach and travel in the bloodstream, eventually getting lodged in a blood vessel and blocking the blood supply to a vital organ such as the heart, brain or lungs.
Some conditions carry an increased risk of blood clots forming inside the blood vessels. This is usually due to a disturbance in the blood flow within the blood vessels. For example, fatty deposits on the walls of the blood vessels (atherosclerosis), or slow blood flow in the leg and pelvic veins can disrupt blood flow, giving a tendency for platelets to clump together and start off the clotting process.
A type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. Heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. Blood clots that develop in the heart can detach and travel to the brain, causing a stroke.
How does it work?
The blood clotting process is complicated. It begins when blood cells called platelets clump together and produce chemicals that activate clotting factors in the blood.
Clotting factors are proteins that are produced by the liver. Vitamin K is essential for their production. The activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. Fibrin binds the platelets together, forming a blood clot.
Warfarin works by reducing the action of vitamin K, which prevents the production of the clotting factors. Without the clotting factors, fibrinogen can't be converted into fibrin and this makes the blood less able to clot.
The anticoagulant effect of warfarin is measured in terms of the prothombin time, which is the time taken for a sample of blood to clot. This time is expressed as the International Normalised Ratio (INR).
How long does it take to work?
Warfarin takes about three days to build up its full anticoagulant effect. This is because it takes about this long for existing clotting factors to be used up. For this reason, when treating blood clots such as deep vein thrombosis (DVT) or pulmonary embolism, a faster-acting injected anticoagulant, such as a heparin, is often used to begin with as well.
A course of treatment with warfarin is usually needed for between six weeks and three months to treat a blood clot. Some people may need to keep taking it on a long-term basis to prevent blood clots.
Size : 100 tablets / box