Contains two active ingredients, Betamethasone and Calcipotriol.
Calcipotriol is a medicine that is a derivative of vitamin D. When applied to the skin it works by reducing the production of skin cells.
In psoriasis, the scaling and thickening of the skin and the appearance of raised plaques are the result of excessive skin cell production. Calcipotriol reduces the excessive skin cell production and promotes normal skin cell growth. This helps flatten and clear the psoriasis plaques.
Betamethasone is a type of medicine called a topical corticosteroid. Corticosteroids are medicines used for reducing inflammation. Skin inflammation in psoriasis occurs due to the irritation of the skin, and is caused by the release of various substances important in the immune system. These substances cause blood vessels to widen, resulting in the affected area becoming red, swollen, itchy and painful.
When betamethasone is applied to the skin it works by acting inside the cells to decrease the release of these inflammatory substances. This reduces swelling, redness and itch. There is a range of strengths of corticosteroids for application to the skin. Daivobet ointment contains betamethasone dipropionate 0.05% and is classed as a potent corticosteroid.
The combination of medicines in this ointment is used to treat stable plaque psoriasis. The ointment should be applied once a day, initially for four weeks. If your psoriasis gets worse again after you stop treatment another course of the medicine can used after a four week break. However, repeated or prolonged treatment must only be used on the advice and under the supervision of your doctor.
What is it used for?
Stable plaque psoriasis vulgaris.
Not to be used in:
Erythrodermic, exfoliative or pustular psoriasis.
People with disorders of calcium metabolism in the body.
Severe liver disease.
Severe kidney disease.
Bacterial skin infections, such as impetigo.
Fungal skin infections, eg athlete's foot, ringworm, candida skin infections.
Viral skin infections such as chickenpox or herpes simplex.
Skin infected with parasites, eg scabies.
Tuberculosis affecting the skin.
Skin sores caused by syphilis.
Inflammatory rash around the mouth (perioral dermatitis).
Dryness and fish skin-like scaling of the skin (ichthyosis).
Areas of skin that are very thin and fragile or have broken veins.
Skin ulcers or wounds.
Itchy skin around the genitals or anus.
Size : 15 g /tube