Celebrex 400 mg
3 or more : $133.99 6 or more : $132.99 12 or more : $130.99
- Brand: Pfizer
- Product Code: PZ_CLB400
- Availability: In Stock
Contain the active ingredient : Celecoxib, which is a type of medicine known as a non-steroidal anti-inflammatory drug (NSAID). Celecoxib capsules are also available without a brand name, ie as the generic medicine.
NSAIDs work by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in producing prostaglandins, in response to injury or certain diseases. These prostaglandins cause pain, swelling and inflammation. Because NSAIDs block the production of these prostaglandins, they are effective at relieving pain and inflammation.
Cyclo-oxygenase does not only produce prostaglandins that cause inflammation. It also produces prostaglandins that have useful roles in the body. There are two different forms of cyclo-oxygenase, COX-1 and COX-2. COX-2 is the form that (among other things) produces prostaglandins that cause inflammation. COX-1 does not produce inflammatory prostaglandins, but does produce others that have useful effects, including some that are involved in maintaining a healthy stomach and intestinal lining.
Traditional NSAIDs, such as ibuprofen or diclofenac, block the action of both COX-1 and COX-2, and this is why they can sometimes cause side effects such as stomach irritation and peptic ulcers. Celecoxib belongs to a new generation of NSAIDs that selectively block the action of COX-2. This means that it stops the production of inflammatory prostaglandins, without stopping the production of prostaglandins that protect the stomach and intestines. It therefore reduces pain and inflammation, but is less likely than traditional NSAIDs to cause side effects on the stomach and intestines (although such side effects are still possible).
What is it used for?
Celebrex is used to reduce inflammation and pain in the following conditions:
A form of arthritis affecting the joints of the spine (ankylosing spondylitis).
English instruction leaflet inside the box.
Size : 60 tablets / box