contain 2 active ingredients: Brimonidine Tartrate and Timolol Maleate. These are both medicines that decrease raised pressure within the eye. They work in different ways to produce a combined effect greater than either medicine produces on its own.
The pressure within the eyeball is naturally maintained by a continuous flow of liquid called aqueous humour through the eyeball. Aqueous humour is produced by a part of the eye called the ciliary body. It drains out of the eyeball through channels called the trabecular meshwork. If the outflow of aqueous humour is blocked, as in glaucoma, the aqueous humour builds up inside the eye, increasing the pressure within the eyeball. This pressure needs to be reduced, as otherwise it can damage the optic nerve and impair vision as a result.
Brimonidine is a type of medicine called an alpha agonist. It works by stimulating alpha receptors found on the blood vessels that supply the ciliary body. This causes the blood vessels to constrict, and reduces the amount of watery fluid that filters out of the blood vessels to form aqueous humour. Brimonidine therefore works by reducing the inflow of aqueous humour into the eyeball, which decreases the pressure within the eye.
Timolol is a type of medicine called a beta-blocker. These medicines block beta-receptors in various parts of the body. Blocking the beta receptors in the eye reduces the amount of aqueous humour that is produced. Timolol therefore also reduces the inflow of aqueous humour into the eyeball and so decreases the pressure within the eye.
The combination of these two medicines is used to lower the pressure in the eye when a beta-blocker eye drop does not lower the pressure enough on its own.
Eye drops are used to produce a local effect in the eye, with minimal effect on other parts of the body. You can further minimise the amount of medicine that is absorbed into your bloodstream and increase the local action in the eye by pressing on your tear duct (the corner of the eye closest to the nose) while putting in the eye drops and for a minute after.
What is it used for?
Open angle glaucoma.
Raised pressure in the eye (ocular hypertension).
Size : 5 ml
English instruction inside the box