Contain the active ingredient : Telmisartan 40 mg & Hydrochlorothiazide 12.5 mgHydrochlorothiazide is a type of medicine known as a thiazide diuretic. Thiazide diuretics act in the kidneys, where they increase the production of urine. They work by causing the kidneys to increase the amount of salts, such as potassium and sodium, that are filtered out of the blood and into the urine. When these salts are filtered out of the blood by the kidneys, water is also drawn alongside. As hydrochlorothiazide increases the removal of salts from the blood, it also causes more water to be drawn out of the blood and into the urine.
Removing water from the blood decreases the volume of fluid circulating through the blood vessels, which decreases the pressure within the blood vessels. Hydrochlorothiazide therefore lowers blood pressure.
Telmisartan is a type of medicine called an angiotensin II receptor antagonist. It works by preventing the action of a hormone in the body called angiotensin II.
Angiotensin II normally acts on special receptors in the body, with two main results. Firstly, it causes the peripheral blood vessels to narrow, and secondly, it stimulates the production of another hormone called aldosterone. Aldosterone causes salt and water to be retained by the kidneys, which increases the volume of fluid in the blood vessels.
Telmisartan blocks the receptors that angiotensin II acts on, and so prevents its actions. The main result of this is that the peripheral blood vessels are allowed to widen, which means that there is more space and less resistance in these blood vessels. This lowers the pressure inside the blood vessels.
Blocking the actions of angiotensin II also reduces the action of aldosterone on the kidneys. The result of this is an increase in the amount of fluid removed from the blood by the kidneys. This decreases the amount of fluid in the blood vessels, which also lessens the resistance and pressure in the blood vessels.
Telmisartan and hydrochlorothiazide have an additive effect on lowering blood pressure. They are used to treat high blood pressure in people whose blood pressure is not adequately controlled on one of the medicines alone.
What is it used for?
High blood pressure with no known cause (essential hypertension).
English instruction leaflet inside the box.
Size: 30 tablets /box