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Trajenta Duo

3 or more : $61.99 6 or more : $60.99 12 or more : $59.99
Tags: Trajenta Duo

Contain 2 active ingredients : Linagliptin and Metformin. These are both medicines used to help control blood sugar levels in people with type 2 diabetes.

In type 2 diabetes the cells in the body become resistant to the action of insulin. Insulin is the main hormone responsible for controlling the level of sugar (glucose) in the blood. It makes cells in the body remove sugar from the blood. When the cells are resistant to insulin this makes blood sugar levels rise too high.

Metformin is a type of antidiabetic medicine known as a biguanide. It works in a number of ways to decrease the amount of sugar in the blood. Firstly, it reduces the amount of sugar produced by cells in the liver. Secondly, it increases the sensitivity of muscle cells to insulin. This enables these cells to remove sugar from the blood more effectively. Finally, it also delays absorption of sugar from the intestines into the bloodstream after eating so that there is less of a spike in blood sugar levels after meals.

Linagliptin is a type of antidiabetic medicine known as a dipeptidyl peptidase-4 (DPP-4) inhibitor. It helps to reduce blood sugar levels by preventing the breakdown of two incretin hormones, called glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP). These hormones are normally produced naturally by the body in response to food intake. They stimulate the pancreas to produce insulin in response to increasing levels of glucose in the blood, and they also reduce the production of glucagon, which is a hormone that normally increases glucose production by the liver. These actions help control blood sugar levels. By stopping the breakdown of these hormones in the body linagliptin increases their effect on controlling blood sugar.

This combination of medicines helps control blood sugar levels both directly after meals and between meals.

What is it used for?

Type 2 diabetes (non-insulin dependent diabetes) in adults aged 18 years and over.

Use in people with type 2 diabetes whose blood sugar is not controlled by the maximum tolerated dose of metformin alone or who are already taking metformin and linagliptin as separate tablets.

They are also licensed for use in combination with a sulphonylurea medicine (eg gliclazide) when one of these combined with metformin has not controlled blood sugar well enough.

Size : 60 tablets / box