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One-Alpha 0.25 mcg

3 or more : $42.99 6 or more : $41.99 12 or more : $40.99
  • Brand: LEO Pharma
  • Product Code: LP_OA_025
  • Availability: In Stock
Contain the active ingredient : Alfacalcidol, which is a form of vitamin D.

Vitamin D is normally obtained primarily from sunlight acting on the skin. It is also consumed in the diet in oily fish and milk products. This vitamin is converted first in the liver and then in the kidneys to its active form, calcitriol. Calcitriol acts as a hormone in the body, controlling the absorption of calcium and phosphate from the gut, the levels of calcium and phosphate in the blood and the normal healthy turnover of bone.

People who have reduced kidney function can't convert enough vitamin D into calcitriol. This can lead to problems with calcium and phosphate metabolism, reduced absorption of calcium and phosphate from the gut, low levels of calcium in the blood and various bone disorders.

Standard vitamin D supplements are no use for people with reduced kidney function, because their kidneys can't convert the vitamin into its active form. However, alfacalcidol is rapidly converted in the liver directly to calcitriol. This bypasses the step required by the kidneys and means the vitamin can then be used by the body. Taking alfacalcidol increases the amount of active vitamin D in the body, which in turn increases the level of calcium and phosphate in the blood and helps reduce bone breakdown.

Alfacalcidol is also given to provide a more rapid increase in active vitamin D and hence calcium, in people with various bone diseases. As this form of vitamin D only requires one conversion to become calcitriol, it provides a quicker response than giving normal dietary vitamin D supplements.

What is it used for?

Correcting calcium levels and weakening of bone caused by kidney failure (renal osteodystrophy).

Softening of the bones due to lack of vitamin D and hence calcium in the body (rickets and osteomalacia).

Correcting the level of calcium in the blood in people who have overactive or underactive parathyroid glands (hypo or hyperparathyroidism).

These glands produce parathyroid hormone, which helps control the metabolism of calcium and phosphate in the body.

Correcting low blood calcium levels (hypocalcaemia) in newborn babies.

Size : 100 tablets / box