Contain the active ingredient : Agomelatine, which is a type of medicine called an antidepressant. It works in a different way to other antidepressants.
Agomelatine works mainly by mimicking the action of melatonin in the brain. Melatonin is a hormone made by the pineal gland, a structure in the brain. It is normally released soon after it starts to get dark. The amount produced then increases until about four am, before dropping off again. Melatonin helps control circadian rhythms and promotes sleep.
By mimicking the action of melatonin, agomelatine helps to re-synchronise the body's circadian rhythms. These include not only sleep/wake cycles, but also mood, anxiety, appetite and body temperature. These circadian rhythms, particularly sleep cycles, are severely disturbed in people with depression. Agomelatine's main action is to improve the onset and quality of sleep and this in turn has an antidepressant effect.
Agomelatine also helps to improve mood in depression by increasing noradrenaline and dopamine release in the brain. These are natural chemicals called neurotransmitters that are involved, amongst other things, in regulating mood.
Agomelatine won't change your personality or make you feel instantly happy. It works over time to correct the chemical changes in your brain that have made you become depressed, and gets you back to feeling like your old self.
What is it used for?
Treat depression in adults.
English instruction leaflet inside the box.
Size : 28 tablets / box